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Diabetes and Management of Lipid Level Following PCI in Acute Coronary Syndrome Patients.
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| Author:
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UPLOADED BY-ADMIN, PATEL JP, PARIKH KH, PATEL JC, KAREN HD, ANAND IS, SHAH JS
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| Abstract:
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Elevated low-density lipoprotein (LDL) cholesterol is a major cause of coronary heart
disease. Although national guidelines for cholesterol management have existed since 1988,
many patients with elevated cholesterol do not achieve their target cholesterol with treatment.
Our aim was to identify the rate of lipid control. It was observational cohort study of 133 patients
who underwent Percutaneous Coronary Intervention, who were investigated for their
lipid profile at 30±7 days. The presence of diabetes and hypertension were added as a risk
factor. The patients mean age, diabetics and hypertensive were 55.73yrs, 45(33.83%),
61(45.86%) respectively. Monotherapy was prescribed in 99(74.43%) patients, while
32(24.07%) were treated with combination of therapy. Only 2(1.50%) patients were not given
any hypolipidemic therapy. The dose of statin 80 mg, 40mg and 10mg were given to
91(68.42%), 35(26.31%) and 4(3.0%) patients respectively. The statin was not given to
3(1.25%) patients. Low Density Lipoprotein Cholesterol (LDL-C) <70mg/dl in 111(83.45%)
patients. While High Density Lipoprotein Cholesterol (HDL-C) >40mg/dl in 48(36.09%),
Serum Triglyceride <150mg/dl in 110(82.70%), serum cholesterol was less than 160mg/dl in
124(93.23%) and Very Low density Lipoprotein (VLDL) was found less than 30mg/dl in
110(82.70%) patients. Acceptable lipid profile control was achieved and the majority of Coronary
Heart Disease (CHD) patients were on lipid lowering therapy in high dose, which indicate
current prescription guidelines is followed but present therapy seems to be inadequate
in raising HDL-cholesterol.
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| Keyword:
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Elevated low-density lipoprotein (LDL) cholesterol is a major cause of coronary heart
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