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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Estimation of Insulin-Like Growth Factor System in Iraqi Children with Hypothyroidism

Author: , , AMAL RASHEED FARHAN
Abstract: To evaluate IGF-1,IGFBP-3,GH in children with hypothyroidism and to predict dwarfism hypothyroidism in children. Total of (25) children with hypothyroidism and (20) healthy children were including in the present study. Serum IGF-1, IGFBP-3 ,growth hormone were measured. Serum IGFBP-1 significantly decrease in hypothyroidism patients when compare to control (p?0.05). There were a significant difference in Growth hormone and IGF-1 levels when compared between hypothyroidism and healthy groups (p?0.05).All parameters of IGF-1 system significantly decrease in hypothyroidism patients the lack in thyroid hormone levels may effected on the growth processing
Keyword: Hypothyroidism , IGF-1, IGFPB-3, GH, dwarfism
EOI: http://eoi.citefactor.org/10.11209/ijpr.10.03.003
DOI: https://doi.org/10.31838/ijpr/2018.10.03.032
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0.12
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