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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Biochemical, hematological and histological effect of Spondias mombin L fruit juice on some physiological properties of Wistar rats

Author: AKHARAIYI COOLBORN*, OKAFOR AUTHOR CHINEDU, OBISESAN ABIOLA OLOWATOSIN, OLAJUYIGBE AKINJIDE BAYODE, JOHNSON JONATHAN ABIDEMI
Abstract: Ripe fruits of Spondias mombin are eaten as mild laxative, diuretic, ice cream, cool beverages, jams, wine, and also of medicinal and industrial uses world widely. Different concentrations (15, 50, 80 and 100%) of crude fruit juice of S. mombin and E. coli Serotype 0157:H7 were separately fed to rats for three days. The blood of rats was taken for haematological analysis, liver and kidney for biochemical assay and histopathological study. Positive control rats were allowed only to rat feed and water while negative control group of rats were infected with pathogenic Escherichia coli. The juice was found not toxic to the rats even at concentration of 100%. Significant increase (P<0.05) in biochemical and haematological levels were observed in the positive control. The crude juice on the biochemical and haematology of rats proved beneficial and also proved save on the liver and kidney of rats.
Keyword: Acute toxicity. Physiological properties. Rats. Spondias mombin. Health.
EOI: http://eoi.citefactor.org/10.11209/ijpr.10.03
DOI: https://doi.org/10.31838/ijpr/2018.10.03.066
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0.12
2018CiteScore
 
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