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Biochemical, hematological and histological effect of Spondias mombin L fruit juice on some physiological properties of Wistar rats
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| Author:
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AKHARAIYI COOLBORN*, OKAFOR AUTHOR CHINEDU, OBISESAN ABIOLA OLOWATOSIN, OLAJUYIGBE AKINJIDE BAYODE, JOHNSON JONATHAN ABIDEMI
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| Abstract:
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Ripe fruits of Spondias mombin are eaten as mild laxative, diuretic, ice cream, cool beverages, jams, wine, and
also of medicinal and industrial uses world widely. Different concentrations (15, 50, 80 and 100%) of crude
fruit juice of S. mombin and E. coli Serotype 0157:H7 were separately fed to rats for three days. The blood of
rats was taken for haematological analysis, liver and kidney for biochemical assay and histopathological study.
Positive control rats were allowed only to rat feed and water while negative control group of rats were
infected with pathogenic Escherichia coli. The juice was found not toxic to the rats even at concentration of
100%. Significant increase (P<0.05) in biochemical and haematological levels were observed in the positive
control. The crude juice on the biochemical and haematology of rats proved beneficial and also proved save on
the liver and kidney of rats.
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| Keyword:
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Acute toxicity. Physiological properties. Rats. Spondias mombin. Health.
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| EOI:
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http://eoi.citefactor.org/10.11209/ijpr.10.03
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| DOI:
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https://doi.org/10.31838/ijpr/2018.10.03.066
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| Download:
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