IJPR  articles are Indexed in SCOPUSClick Here     Impact Factor for Five Years is 0.13 (2013 - 2018).    

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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

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0975-2366
5 - Years Impact Factor

Year 2012 - 2016

Impact Factor: 1.55

Total Publications: 317

Total Citation: 491

Year 2011 - 2015

Impact Factor: 1.46

Total Publications: 326

Total Citation: 477

Year 2010 - 2014

Impact Factor: 1.3

Total Publications: 313

Total Citation: 407

Year 2009 - 2013

Impact Factor: 0.973

Total Publications: 293

Total Citation: 285

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January - March 6 [1] 2014

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PIPPHARMACON & IJPR 2018

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OXIDATION OF QUETIAPINE BY POTASSIUM DICHROMATE IN ACID MEDIUM: A KINETIC STUDY

Author: SAYYED HUSSAIN*, SYED YOUSUFHUSSAIN, GULAM FAROOQ MUSTAFA, SAYYED SALIM
Abstract: Kinetics of oxidation of quetiapine using potassium dichromate as oxidizing agent in acid medium was studied spectrophotometrically at 520 nm. The result interprets that rate of oxidation is first order with respect to potassium dichromate and quetiapine where as it does not depend on the concentration of acid. The stoichiometry of the reaction was found that one mole of oxidant is consumed for oxidation of three moles of quetiapine and the product found is quetiapine N-oxide. From the results of kinetic studies, reaction stoichiometry and product analysis with suitable mechanism of the reaction was proposed. Based on results of the reaction at different temperatures, the activation parameters with respect to the slow step of the proposed mechanism was calculated.
Keyword: Kinetics, Oxidation, Quetiapine, Potassium Dichromate
DOI: https://doi.org/10.31838/ijpr/2018.10.03.075
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0.07
2017CiteScore
 
11th percentile
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Impact Factor for five years is 1.55 (2012 - 2016)

Year 2011 - 2015 Impact Factor - 1.46 Total Publications - 326 Total Citations - 477