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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

Published by : Advanced Scientific Research
ISSN
0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Antioxidant Activities of Ethyl Acetic Extract of Endophytic Fungi from Caesalpinia sappan L. and Eucheuma sp.

Author: H HAFSAN*, EKA SUKMAWATY, MASHURI MASRI, , ISNA RASDIANAH AZIZ, , SITI LATIFAH WULANDARI
Abstract: Antioxidants act as an antidote to free radicals in the body and prevent various diseases caused by oxidative stress. Endophytic fungi are currently assuming as a promising source of antioxidant compounds to replace synthetic antioxidants. This study was aimed to determine the antioxidant activity of endophytic fungi isolated from sappan wood (Caesalpinia sappan L.) and Macro algae Eucheuma sp., to determine the antioxidant activity of the consortium both of fungal isolates. Antioxidant activity was determined by free radical reduction method using DPPH. The results showed that five isolates of endophytic fungi isolated from sappan wood were Curvularia lunata, Penicillium sp., Chrysosporium sp., Trichoderma sp. and Geotrichum candidum. One isolate from Eucheumasp., namely Aspergillus sp. The highest antioxidant activity was found inTrichoderma sp. and Aspergillus sp. which IC50pointwere 46.354 and 38.64 respectively. The consortium was able to increase the antioxidant activity of single isolates which the lowest IC50.
Keyword: antioxidant,Caesalpinia sappanL., DPPH, Eucheuma sp., endophytic fungi
DOI: https://doi.org/10.31838/ijpr/2018.10.03.078
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0.12
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