IJPR  articles are Indexed in SCOPUSClick Here     Impact Factor for Five Years is 0.13 (2013 - 2018).    

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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence

IJPR included in UGC-Approved List of Journals - Ref. No. is SL. No. 4812 & J. No. 63703

ISSN
0975-2366
5 - Years Impact Factor

Year 2012 - 2016

Impact Factor: 1.55

Total Publications: 317

Total Citation: 491

Year 2011 - 2015

Impact Factor: 1.46

Total Publications: 326

Total Citation: 477

Year 2010 - 2014

Impact Factor: 1.3

Total Publications: 313

Total Citation: 407

Year 2009 - 2013

Impact Factor: 0.973

Total Publications: 293

Total Citation: 285

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Article Detail

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Effects of Liver Cancer Drugs on Cellular Energy Metabolism in Hepatocellular Carcinoma Cells

Author: MANU KANTI, SOMNATH ROY, DEBABRATA SAMANTA
Abstract: Liver cancer is the major cause of death among various types of cancer all around the world. Liver has several functions such as secretion of bile juice into the intestine for the absorption of the fats, liver is also involved in the manufacturing of the blood clotting factors that are needed to stop the bleeding. In this paper we have put an effort to study the effects of drugs which are used for the treatment of hepatocellular carcinoma cells and their influence on the metabolic pathways, specifically on aerobic glycolysis and oxygen consumption by tumour cells to meet their energy demand also we have discussed growth tumors with respect to temperature.
Keyword: ATP depletion, Glycolysis, Hepatotoxins, Hypoglysemic effect, Liver cancer, Mitochondrial inner membrane potential, Oxidative phosphorylation.
DOI: https://doi.org/10.31838/ijpr/2018.10.03.079
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0.07
2017CiteScore
 
11th percentile
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Impact Factor for five years is 1.55 (2012 - 2016)

Year 2011 - 2015 Impact Factor - 1.46 Total Publications - 326 Total Citations - 477