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Effects of Long Term Administration of Echinacea in Addition with Vaccination on General Condition and Liver and Renal Performance in Dogs
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| Author:
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YASAMAN BIAZAR*, REZA AVIZEH, MASOUD GHORBANPOUR, HOSSEIN NAJAFZADEH VARZI, MOHAMMAD RAZIJALALI
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| Abstract:
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Echinacea is one of the more recognized herbs associated with immune modulation in human and animals. Until now
little work has been done to evaluate its effects in dogs. The aim of this study was to evaluate the effects of long-term
administration of Echinacea on some biochemical and hematological parameters in dogs. For this purpose, 15 adult
healthy dogs of mixed breed were divided into three equal groups. Dogs in group 1 received orally extract of
Echinacea purpura for a period of 28 days and canine polyvalent vaccine on the seventh day.Dogs in groups 2 and 3
received Echinacea purpura and canine polyvalent vaccine, respectively, at values similar to those of group 1.On days 0,
28 and 56 days after Echinacea feeding, blood samples were collected from all dogs and serum hematologic and
biochemical parameters including alanine aminotransferase, aspartate aminotransferase, blood urea nitrogen,
creatinine, albumin and total protein were measured.Echinacea increased significantly the number of red and white
blood cells as well as lymphocytes and hemoglobin and also significantly decreased the number of neutrophils
(p<0.05). Vaccination alone resulted in a significant increase in white blood cell count (p<0.05). This study proved that
long-term feeding of Echinacea in dogs while increased blood parameters, especially the red blood cells, had no
complications and toxicity on hematologic and biochemical parameters.
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| Keyword:
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Echinacea, Vaccination, Hematology, Biochemistry, Dog
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2018.10.04.054
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| Download:
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