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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Assessment the immune response in patients with renal failure

Author: NA'EEMA AL-DULAIMY, ALAA JAWAD HASSAN, JAAFAR KHALAF ALI
Abstract: Renal failure is a condition in which the kidneys fail to remove and concentrate metabolic end products from the blood, regulate the fluid, electrolytes, and pH balance of the extracellular fluids. The underlying cause may be renal disease, systemic disease, and/or urologic defects of non-renal origin. Renal failure can occur as an acute or a chronic disorder. A descriptive study was conducting to evaluate the immune response for patients with renal failure by determine the levels of Anti-ds-DNA, ANA, C3 and C4.A purposive samples of forty patients with renal failure and twenty healthy. The blood samples were assembling and they were tested by using the special detectors to identify the levels of ANA, Anti-ds-DNA, C3 and C4. Of this study showed that there was a significant difference (increase) between control group and patients group in relation to ANA and Anti-ds-DNA. And there was low levels of C3 and C4 in patients group in contrast with control group. In this study can conclude that there are high level of ANA and Anti-ds-DNA and low level of C# and C4 in renal failure patients.
Keyword: Renal failure, Anti-ds-DNA, ANA, C3, C4
DOI: https://doi.org/10.31838/ijpr/2018.10.04.077
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