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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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CORRELATION OF SERUM COPPER, ZINC, MAGNESIUM WITH INSULIN RESISTANCE IN PCOSFEMALE OF REPRODUCTIVE AGE GROUP

Author: REVATHI. *,, JULIUS. A, SWETHA SINGARAVELU
Abstract: Background: Insulin resistance is communal in patients with PCOS-Polycystic Ovary Syndrome.Serum copper, zinc, magnesium are measured and it is correlatedwith insulin resistance.Aim of Study: The present study intended to determine correlations among insulinResistance and minerals like copper, zinc, magnesium inpatients with PCOS. Methodology: The subjects were identified from gynecology OPD of private medical college in Tamilnadu.The study involved 200 femaleof age 15-45 years (100female had PCOS and the other 100 female werecontrols).Results: HOMA wasmeaningfully higher in female with PCOS in contrast withControl. There was a significant correlation of copper, zinc and magnesium with insulin resistance. It was observed that the levels of copper and zinc increases with patient showing insulin resistance while magnesium was lowered in the same.Conclusion:There is a significant correlation between the levels of copper, zinc, magnesium and IR in patients with PCOS.
Keyword: Copper, zinc, magnesium, HOMAIR,PCOS.
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