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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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PHYTOCHEMICAL CONTENT AND ANTIMICROBIAL POTENTIAL AGAINST FOODBORNE AND SPOILAGE BACTERIA OF EXTRACTS FROM Areca Catechu and Passiflora edulis

Author: NIK FAZNI, MUHAMMAD HILMI SHAIRAZI, NOOR NADIA SYAHIRA MOHD KAMAL, PUTERI NUR ALIAH WAN FAIZAL, ANIS LOW MOHAMMAD LOW, NUR INTAN HASBULLAH, SHARIFAH AMINAH SYED MOHAMAD
Abstract: This study is designed to investigate the phytochemical compound and antimicrobial activity of Areca catechu (betel) nut and Passiflora edulis var. Flavicarpa Degenerer (Passion fruit) against foodborne and spoilage bacteria. The screening of phytochemical compound of betel nut extracts showed that phenols, tannins, flavonoids and glycosides were the most common phytochemical compounds extracted. For antimicrobial activity, the most excellent bioactivity is demonstrated by methanolic extract for both Areca catechu and Passiflora edulis var. Flavicarpa Degenerer. The highest inhibition zone was demonstrated by methanol extract of leaves from P.edulis showed 13mm and for A.catechu, the young nut which showed the highest inhibition zone which is 11 mm zone of inhibition. From the result, methanol extracts of A. catechu young and old nut showed substantial MIC value with the lowest concentration required was 6.25 mg/ml to inhibit the tested bacteria. The highest value of MIC was 0.78 mg/ml by methanol extract of both young and old nut of A. catechu against S. aureus. For the P.edulis, the highest value for MIC is 0.8 mg/ml and the lowest value is 200mg/ml.
Keyword: ONM: old nut methanol, YNM: young nut methanol
DOI: https://doi.org/10.31838/ijpr/2018.10.04.007
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