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Synthesis,characterization and Toxicological study for some new Compoundsderivedfrom(2E)-1,2- diphenyl-2-(phenylimino)ethan-1-one mercuric chloride and amino acidsin Musmusculusmice
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| Author:
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JAMAL HARBI.AL-SAADIAND , NUHAHUSSEIN.AL-SAADAWY
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| Abstract:
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(2E)-1,2-diphenyl-2-(phenylimino)ethan-1-one mercuricchloride Prepared from reacting between(Benzil andP-amino
phenyl mercury chlorid) with1:1 mole ratio then product (2-{(E)-[(2E)-1,2-diphenyl-2-
(phenylimino)ethylidene]amino}propanoicacid mercuricchloride) and(2-{(E)-(2E)-1,2-Diphenyl-2-phenyliminoethylideneamino)-
3-(1H-indol-3-yl)-propionic acid mercricchloride) ,reacted with amino acids such asalanin and
troptophan with also 1:1 molar ratio.all prepared compounds was agreement with mass spectroscopy ,1HNMR, FT-IR
Resuits.Toxicity studies carried in Musmusculusmice .The LD50 Values measurement by karber method, using different
compounds dose (10 ,20 ,50 ,100 and 150)mg/kg BW ,were injected (IP) to the varionsgroups of mice ,LD50 of N1 was
(102.5) and LD50 of N2 was (104.17) .
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| Keyword:
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OrganomercuryCompounsd,amino acids ,LD50
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2019.11.01.063
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| Download:
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