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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Detection and Comparative Study of Human Herpesviruses 6,7 and Cytomegalovirusin Patients with brain tumors.

Author: AL-SHERIFY M, MUSA NIMAMEZHER, MAYADAFARHANDARWESH
Abstract: This study included 115 patients confirmed with brain tumor 69(60%)male and 46 (40%) female ; with age ranged between 2-85years old.It revealed that the highest percentage age group was (<25) years 43(38%).Benign tumor counted about (19.4%) of studed patients while Malignant assessed about (80.6%). Meningioma represent the most prevalente type: 24(35%) ,Gliomas 16 (24%) :{Astrocytoma 10 (15%) , Ependymoma 4(6%) and Oligodendroglioma 2 (6%)}, Glioblastoma multy form (GBM) 14(21%) ,Schwannoma 5(7%), Germinoma 3(5%) and Medulloma 2(3%), And other BT types assessed (4%). Beta-Human Herpe virus was detected by nested (PCR) . The present results reflected that from (68 tested) patients were without viral incidences 26/68 (39%) while most patientsinfected with one or more of viruses (61%) as the following [ HCMV(52%) , HHV-6 29(43%) and HHV-7 20(29%)].Super infections distribution was assessed as following [(HCMV+HH-6) 23 (34%) , (HCMV+HHV-7) 16 (24%) , (HHV-6+7) 10( 14%)].
Keyword: Human herpesvirus - 6,7,HumanCytomegalovirus,Brain Tumors Risk factors ,Neurotopism.
DOI: https://doi.org/10.31838/ijpr/2019.11.02.012
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