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Synthesis and Evaluation of Some N-Substituted 2,5-dimethyl pyrroles as Anthelmintics and Antibacterials
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| Author:
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SANTOSH GAONKAR, NAMRATHA B, NITINKUMAR S. SHETTY
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| Abstract:
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A library of N-substituted 2,5-dimethylpyrroles were synthesized from aromatic hydrazides/an amine using saccharin as a green catalyst. The target compounds were screened for their efficacy as anthelmintics and antibacterials in vitro. The results revealed that, compounds 2a, 2b, 2e, 2i, 2k, and 2m were potent anthelmintics with compounds 2a, 2b, and 2k being potent antibacterials.
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| Keyword:
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anthelmintic, antibacterial, nitroscanate, pyrrole
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| EOI:
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-
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| DOI:
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-
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| Download:
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