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Amalgamated Vitro Anti-Malarial Development of 4-Quinazolinone Derivatives Using QSAR Investigation
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| Author:
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ALLEN TILAK J., PARTHASARATHY M. P, DR. J. VENKATESWARA RAO, DR M ADITYA KRISHNA
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| Abstract:
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Malaria is a dismissed tropical parasitic ailment influencing billons of individuals around the world. In spite of the fact that the quantity of cases and passing’s related with Malaria are diminishing lately, it is the most destructive infection on the planet. Normal item oversees a significant function in the advancement of novel medications against a few infections. A wide scope of semi engineered and manufactured analogs of common item till utilized as an enemy of malarial, hostile to disease medicates, etc. It is notable to us that Malaria is turning into a hazardous issue now daily in light of its on-going safe upon ordinary antimalarial drugs. In the current examination we select a strong enemy of malarial common item Febrifugine got from Dichroafebrifuga and blended some amide subsidiary. After ensuing pharmacological advancement we performed 3D QSAR investigation to decide the basic knowledge of these sort of atoms for their antimalarial property.
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| Keyword:
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Febrifugine, Anti-malarial, 4-Quinazolinone
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2020.SP1.464
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| Download:
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