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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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A review on antivenin activities of indigenous plants against venom of Naja naja

Author: GNANASELVAN SUVATHIKA, THIRUNAVUKKARASU SIVARAMAN
Abstract: Snake venoms are complex mixture of pharmacologically active bio-macromolecules such as peptide and proteins and snakebite could be considered as one of the critical and complicated medical emergencies in tropical and sub-tropical regions as well. Anti-serum venom is the only treatment in allopathy to snakebite envenomation and the treatment has its own limitations from technical and clinical standpoints. Interestingly, from time immemorial, ethnobotanical systems have supposedly given effective treatments for snakebite as inferred from folklore and quite a number of indigenous plants have been shown to possess the antivenom properties using in vitro, ex vivo and in vivo methods by various eminent research groups from national and international level. In this background, we herein discuss about the scopes to explore alternative treatments to anti-snake venom through phytomedicines and as well probable prospect of producing vaccine-like natural products for snakebite to mitigate the ever-increasing human - snake conflicts.
Keyword: Toxinology, Snakebite, Antivenom, Indigenous plants and Human - snake conflicts
DOI: https://doi.org/10.31838/ijpr/2020.SP1.064
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