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Chemical composition, antimicrobial and anticancer activities of essential oils extracted from Nankah seeds usingconventional,microwave assisted hydrodistillation and solvent extraction methods
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| Author:
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EL-SAYED S. ABDEL-HAMEED, SHROQ M. AL-THBITY, ADIL A. GOBOURI
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| Abstract:
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Trachyspermum ammi L. seeds; commonly known as nankah in Kingdom of Saudi Arabia (KSA) and some of Arabic countries; considered as one of important spices used especially as flavor in preparation the famous Saudi beverage, Arabic coffee. In this study, the impact of three extraction methods; conventional hydrodistillation method (HD), microwave assisted hydrodistillation (MAHD) and solvent extraction by n-hexane (HX); were evaluated on the chemical and biological properties of the essential oils of Nankah. The results showed no great difference between the oil yield extracted by HD and MAHD, while the yield by HX was high and this attributed to the presence of other fatty materials with the essential oil components. In spite of the two methods, HD and MAHD gave nearly the same results from qualitative and quantitative analysis, the extraction by MW was rapid, saving time and energy than HD. Essential oils obtained by the three methods showed variable in vitro anticancer, antibacterial and antifungal activity. As well as being environmentally friendly due to energy and time savings, the authors suggest the use of the microwave process in essential oil extraction. The biological results provide the basis for further in vitro and in vivo studies to evaluate the potential use of essential oil from nankah has antimicrobial and anticancer agents in the hope to use this oil in the prevention and therapies of these diseases.
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| Keyword:
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Trachyspermum ammi, nankah, essential oil, microwave, n-hexane,anticancer, antimicrobial.
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2020.SP1.133
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| Download:
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