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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Role of Curcumin an Antiviral Agent

Author: , N.E.KAVIYA, N.P.MURALIDHARAN, ANITHA ROY
Abstract: This review is provided with a detailed overview of the role of curcumin as an antiviral agent. Curcumin is an active ingredient of turmeric used as food additives and therapeutic agent that possess anti-inflammatory, antiviral, antioxidant, anticancer, antifungal activities etc. Curcumin has a wide spectrum of pharmacological and biological properties. Curcumin produces antiviral activity against dengue virus, norovirus, HIV, HSV, HPV etc. Norovirus needs phytochemical activity for cure hence curcumin is preferred. Natural products like curcumin serve as products containing anti-infectives and have good recognition in the prevention, diagnosis and treatment of diseases. Natural products are used as remedies for alternative medicine as they are non-toxic and have no side effects. The main usage of curcumin is it is used in treating abdominal pain. The curcumin acts by modulation of biological processes in disease prevention. The curcumin is an effective nitrogen species and ROS scavenger. The use of plant extract helps in prevention of virus in a safer and cost-efficient manner. Pharmacological uses include atherosclerosis, rheumatoid arthritis, diabetes, ulcer etc. The production of combinations of drugs with curcumin has also increased in the medicinal field. The main drawback of curcumin is its bioavailability. Hence curcumin plays an important role in maintaining the antiviral property against viruses; it inhibits particular viruses at particular sites with particular mechanisms. Modifications in bioavailability are made to make curcumin a more stable antiviral agent.
Keyword: Curcumin; Turmeric; Norovirus; pharmacological use; bioavailability.
DOI: https://doi.org/10.31838/ijpr/2020.SP1.001
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