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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Urinary tract infections in Al-Kufa City Iraq and phenotypic detection of antimicrobial sensitivity pattern of bacterial isolates.

Author: KAREEM GHALI MOHAMED, AHMED ABDULJABBAR JALOOB ALJANABY
Abstract: Background: In many countries, urinary tract infection (UTI) considered as one of the most recurrent problem caused by many types of multi-drug resistance bacteria. Objective: Phenotypic detection of antibiotic susceptibility patterns of gram negative bacteria isolated from patients with urinary tract infection in Al-Kufa City, Iraq. Materials and methods: One hundred and five urine samples were collected from patients infected with UTI. Kirby-Bauer method was done to investigate the antibiotic susceptibility testing for each bacterial isolate. Results: One hundreds of four bacterial strains were grown. Escherichia coli (E.coli) is the most prevalence one 46 (43.8%), Klebsiella pneumoniae (K.pneumoniae) 29 (27.6%), Pseudomonas aeruginosa (P. aeruginosa) 14 (13.3%), Citrobacter freundii (C. freundii) 11 (10.5%) and 5 urine samples (4.8%) were without growth. The antibiotic imipenem had excellent effect against most isolates. While, third generation cephalosporins and amoxicillin provided low antibacterial effect against most bacteria. Conclusions: Urinary tract infection caused by gram negative bacteria became big problem due to their ability to resist many classes of antibiotics. Therefore, must be make antibiotic susceptibility test recurrently to avoid this problem.
Keyword: Phenotypic, Antimicrobials, UTI, E.coli , K.pneumoniae , P. aeruginosa, C. freundii
DOI: https://doi.org/10.31838/ijpr/2020.SP1.222
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