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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Prevalence and risks of somatic diseases among workers of the uranium processing enterprise of Kazakhstan

Author: F.K.BEKENOVA , P.K.KAZYMBET, V.A.TKACHEV, G.S.HUSAINOVA, SH.B.SULEYMENOV
Abstract: The aim of the research was to study the prevalence and relative risks of somatic diseases among the workers of the uranium processing leach plant. A single-point full-design cross-sectional study of 912 leach plant workers was conducted. The experimental group consisted of 778 workers of Stepnogorsk bearing plant, located at a distance of 10 km from the leach plant. Prevalence (Pr), gross relative risks (RR), and standardized relative risks (SRR) of somatic diseases were evaluated. Standardization was carried out by gender, age, length of service. The most common somatic diseases among the leach plant workers were arterial hypertension (Pr=246,7 ‰; 95 % CL 218,7-274,7); chronic obstructive pulmonary disease (Pr=193,0 ‰; 95 % CL 167,4-218,6); chronic gastritis (Pr=174,3 ‰; 95 % CL 149,7-198,9). These same diseases had excessive gross relative risks: for arterial hypertension (AH) RR was 2.4 (95 % CL 1.9-3.0); chronic gastritis (CG) RR = 2.1 (95 % CL 1.6-2.7); chronic obstructive pulmonary disease (COPD) RR =2.0 (95% CL 1.6-2.6). Stratification was carried out by gender, age, length of service and SRR was calculated for major somatic diseases. The SRR for AH was 2,8 (95 % CL 2,1-3,7; ?2=48,8; p<0,001); COPD – 2,5 (95 % CL 1,8-3,4; ?2=34,8; p<0,001); CG – 2,4 (95 % CL 1,7-3,4; ?2=29,0; p<0,001). SRRs were higher than similar RR, which may be associated with a more significant impact on the prevalence of the main somatic pathology among nuclear workers of production factors and requires further study of the influence of radiation-toxic risk factors.
Keyword: : somatic diseases, uranium processing enterprise, relative risks, prevalence, chronic gastritis, arterial hypertension, chronic obstructive pulmonary disease.
DOI: https://doi.org/10.31838/ijpr/2020.SP1.308
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