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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Receptor Binding Domain and accessible Treatments for Corona Virus: A Review

Author: VIKAS SHARMA, SAGAR JOSHI, CHANDANA MAJEE
Abstract: Coronavirus is having a place within the group of coronaviridae, nidovirales and wiedely introduced in people and different warm-blooded creatures. It is wrapped within non divided (positive sense RNA infection). It focuses on the human respiratory system. Toward the finish of 2019 December, an enormous number of pneumonia cases were admitted to the medical clinic with obscure etiology which are legitimately connected with wet market of Wuhan. Contamination time of covid-19 is 6-41 days. As indicated by WHO the underlying side effects of COVID-19 are hack, fever, solid brevity, dyspnea instead of this some patient demonstrated atypical side effects like regurgitating and the runs. Transmission of disease happen when legitimately come in close contact with the early patient with history of presentation of wet market in Wuhan. Coronavirus virions are round to pleomorphic wrapped particles. The envelope is studded with envisioning S glycoproteins of Coronavirus Structure, and includes a middle containing system protein encased inside which is a singular strand of positive-sense RNA. The medicaments which are used by off levels are as follow; Ribavirin, mycophenolic destructive, interferon (IFN, etc. Against HIV drugs like lopinavir, ritonavir, remdesivir and Chloroquine.
Keyword: Corona virus, Nidovirales, pneumonia, glycoproteins
DOI: https://doi.org/10.31838/ijpr/2020.SP1.359
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