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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Chemical Composition and In-Vitro Antioxidant Activity of Angelica glauca Collected from Western Himalayan Region

Author: SWATI , H K. PANDEY, A. SINGH, H.S. MEENA, M. BALA
Abstract: Angelica glauca Edgew is an important medicinal and aromatic herb of family Apiaceae. The roots of the plant are used as condiments and spices. The goal of this study was to investigate the chemical composition and in-vitro antioxidant activity of Angelica glauca roots. The essential oil was isolated from Angelica glauca roots collected from high altitude region of Himachal Pradesh by the hydro-distillation method and subjected to gas chromatography-mass spectrometry (GC/MS). The antioxidant activity of the essential oil, hydroalcoholic and aqueous extracts was carried out by using the ABTS method. GC/MS analysis of essential oil identified 24 different chemical constituents, including limonene (27.95%), Z-ligustilide (23.31) and ß-ocimene (6.95%) as major compounds. The essential oil composition of A. glauca from the selected area of Himachal Pradesh was not reported so far. Antioxidant activity of the hydroalcoholic extract of A. glauca exhibited higher radical scavenging ability as compared to the aqueous extract and essential oil. The essential oil from A. glauca roots identified various important compounds that could serve their role in aromatherapy, nutrition and pharmaceutical industries. The roots of the plant showed potential antioxidant activity and could be used as a nutritional supplement.
Keyword: A. glauca, Essential oil, GC/MS, Antioxidant.
DOI: https://doi.org/10.31838/ijpr/2020.SP1.342
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