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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Extraction, Phytochemical Screening and Spectral Interpretation of Plant Extract of Thunbergia Grandiflora.

Author: MAHESH BABANRAO THORAT, NEETESH KUMAR JAIN, BHUSHAN RAGHUNATH PAWAR, AVINASH SHANKAR BHOSALE
Abstract: Thunbergia grandiflora, widely known as blue trumpet wine, sky vine or sky flower, is considered to have substantial efficacy against non-small cell lung cancers (NSCLC) and antioxidants, owing to the existence of some bioactive compounds such as phenolics and flavonoids. The plant extract has been studied for phytochemical analysis and spectral understanding in present science. Qualitative research has reported significant involvement of phenolic compounds, glycosides, flavonoids, sugars, triterpenoids and steroids of leaves and in ethyl acetate, where sugars and phenols are missing, is found. The complete phenolic compounds and flavonoids in quantities expressed as gallic acid equals and rutin equivalents were also quantitative study. The cumulative phenolic content of ethyl acetate extract was 60.833 in Thunbergia grandiflora and 103.50. The overall flavonoid content of ethyl acetate extract from Thunbergia grandiflora was 60.833 and 103.50 for methanol extract. The overall amount of phenolics and flavonoids in methanol extract was highest. Spectral analysis of fractions by IR and NMR Spectra confirm the existence of benzene, hydroxy and methylene protons. Mass spectrum thus shows that the compound may have a quercetin derivative of 4, 5.
Keyword: Plant Extract, Thunbergia Grandiflora, flavonoids, phenolics.
DOI: https://doi.org/10.31838/ijpr/2020.SP1.392
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