*Five Years Citation in Google scholar (2016 - 2020) is. 1451*   *    IJPR IS INDEXED IN ELSEVIER EMBASE & EBSCO *       

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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

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Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Systematic Review of the Potential of Chitosan as Antibacterial and Anti-inflammatory in the Oral Cavity

Author: HARUN ACHMAD, MARIA TANUMIHARDJA, HENDRASTUTI HANDAYANI, NURUL MUTMAINNAH, YUNITA FEBY RAMADHANY
Abstract: Introduction: Chitosan.is obtained.from deacetylation of chitin bases, and.acetamide.groups are converted into primary amino groups during deacetylation. Chitosan is a biopolymer that has great use in various dental studies. It has been found that chitosan is effective as an antibacterial and anti-inflammatory, for example toothpaste, mouthwash. and root canal irrigation from chitosan. So this systematic review reviews some of the literature on the potential of chitosan as an antibacterial and anti-inflammatory in the oral cavity. Methods: In this systematic review, the articles search was performed on Google Search and Pubmed. Studies published from 2011 to 2020. 155 were articles assessed, including 155 articles from the databases electronic, 0 from the manual search. 96 records screened, 61 records excluded, 35 full-text articles assessed for eligibility and 17 full text articles included. Result: There are 12 articles about antibacterial of chitosan and 5 articles about anti-inflammatory chitosan. Conclusion: Based on 17 articles show that chitosan is very potential as a herbal plant that can be antibacterial and anti-inflammatory in the oral cavity.
Keyword: Chitosan, Antibacterial, Anti-inflammatory, Oral cavity
DOI: https://doi.org/10.31838/ijpr/2020.SP1.399
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