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INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH

A Step Towards Excellence
Published by : Advanced Scientific Research
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0975-2366
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IJPR 9[3] July - September 2017 Special Issue

July - September 9[3] 2017

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Antioxidant and Antibacterial Activity of Silver Nanoparticles Prepared from Horseradish Oil

Author: MONICA ANTONY, ANITHA ROY, S RAJESHKUMAR, DR. LAKSHMI THANGAVELU
Abstract: Aim: To study the antioxidant and antibacterial activity of silver nanoparticles prepared from horseradish oil. Materials and Methodology: Horseradish oil mediated silver nanoparticles were initially synthesised and centrifuged using Lark refrigerator centrifuge. They were characterised by UV-Visible spectrophotometer. Further the horseradish oil mediated AgNPs were subjected to DPPH assay to determine the antioxidant activity. The antibacterial property was also determined using the agar well diffusion method against S.mutans and Lactobacillus and antifungal activity against Candida albicans. Results: Horseradish oil mediated silver nanoparticles were biosynthesised with ease to show good antioxidant and antibacterial activity compared to standard. The antimicrobial activity was analysed against S.mutans and Lactobacillus and Candida albicans and the highest zone of inhibition was 9 mm seen with S.mutans. The antioxidant activity of horseradish oil mediated silver nanoparticles showed a highest percentage of inhibition as 84% at a concentration of 50µL. Conclusion: The biological approach for the synthesis of silver nanoparticles using horseradish oil is an eco-friendly method. The synthesised horseradish mediated silver nanoparticles showed very good antioxidant activity. The antibacterial activity exhibited was minimal. Hence, the study concluded that Horseradish oil mediated silver nanoparticles may be used for its antioxidant property.
Keyword: Horseradish oil, silver, nanoparticles, antioxidant, antibacterial
DOI: https://doi.org/10.31838/ijpr/2020.SP1.406
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