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Antioxidant and Anti-Inflammatory Activity of Selenium Nanoparticle Synthesized Using Tamarind Extract
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| Author:
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SAROJINI RAMYA PILLAY, ANITHA ROY, S.RAJESHKUMAR, DR. LAKSHMI THANGAVELU
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| Abstract:
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Aim: This study aim of the study was to synthesise selenium nanoparticles from tamarind extract and check the antioxidant activity and anti-inflammatory activity of the same.
Materials and Methods: Tamarind mediated selenium nanoparticles were synthesised from (Tamarindus indica) extract. The SeNPs were subjected to DPPH assay where the DPPH free radical scavenging activity of tamarind powder mediated SeNPs was determined. The nanoparticles were evaluated for its anti-inflammatory activity by studying its inhibitory effect on albumin denaturation assay technique.
Results: The selenium nanoparticles were synthesised using tamarind powder and was confirmed by UV-visible spectroscopy. Tamarind powder mediated SeNPs were biosynthesised with ease and showed effective antioxidant and anti-inflammatory activity compared to that of standard. The highest concentration of antioxidant activity of SeNps was found at 50µL at a percentage of 68% and the highest concentration of anti-inflammatory activity of SeNps was found at 50µL at a percentage of 81%.
Conclusion: It can be thus concluded that tamarind powder mediated nanoparticles have the potential to be used as an effective antioxidant and anti-inflammatory. Hence it can be employed in large scale production and be used in many medicinal applications.
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| Keyword:
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Anti-inflammatory; antioxidant; selenium nanoparticle; Tamarindus indica.
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| EOI:
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-
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| DOI:
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https://doi.org/10.31838/ijpr/2020.SP1.413
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| Download:
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