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Anti-Inflammatory Activity of Cynodon Dactylon Aqueous and Aqua Alcoholic Extract
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| Author:
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NEHA. N, S RAJESHKUMAR, V.B PREEJITHA
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| Abstract:
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Introduction: Cynodon dactylon (Bermuda grass) is a grass that originated in Africa. It is a member of the family Poaceae. It is a perennial plant widely used as a valuable source of medicine from traditions. It was traditionally known as durva and was used as a folk remedy for anasarca, cancer, convulsions, epilepsy, hypertension, bronchitis, cough, and diarrhoea. The extracts of this plant have a wide range of applications and have shown promising results in the field of medicine. This study evaluates the anti-inflammatory activity of the aqueous and aqua alcoholic extracts Cynodon dactylon.
Aim: The aim of this study is to evaluate the anti-inflammatory activity of the aqueous and aqua alcoholic extracts of Cynodon dactylon.
Materials and methods: The aqueous and aqua alcoholic extracts were prepared by dissolving the dried form of plant with 100 ml distilled water, distilled water + ethanol (in equal concentrations) respectively. The anti-inflammatory activity of these extracts in different concentrations of 10-50 µl was evaluated using Inhibition of albumin denaturation assay. BSA was used as a reagent for the assay. The same procedure was carried out to check the anti-inflammatory activity of the standard, Diclofenac sodium in different concentrations.
Result: From the % of inhibition of the extracts obtained, it was found that both the extracts showed good anti-inflammatory activity in relation to the standard Diclofenac sodium. In comparison, the aqua alcoholic extract showed better anti-inflammatory activity than aqueous extract.
Conclusion: From the above study, it is evident that both aqueous and aqua alcoholic extracts of C. dactylon possess good anti-inflammatory activity. In addition to the pre-existing medicinal values of this plant, it can be concluded that C. dactylon reveals itself as a promising drug in herbal medicine.
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| Keyword:
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Cynodon dactylon; aqueous extract; aqua-alcoholic extract; anti-inflammatory activity; Diclofenac sodium.
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| EOI:
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| DOI:
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https://doi.org/10.31838/ijpr/2020.SP1.423
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| Download:
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